citrate synthase

By Targets:	Biochemical Assay Reagents (2) Endogenous Metabolite (19) Isotope-Labeled Compounds (8)
By Research Areas:	Cancer (1) Metabolic Disease (2) Neurological Disease (16)

Targets Recommended: ATP Citrate Lyase PGE synthase Thymidylate Synthase ATP Synthase Acetolactate Synthase (ALS) Glucosylceramide Synthase (GCS) NO Synthase Fatty Acid Synthase (FASN) Cyclic GMP-AMP Synthase GSK-3

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents	Cancer
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit **citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀** values of 0.4-1.6 mM .

HY-N0473

L-Tyrosine 1 Publications Verification Tyrosine	Endogenous Metabolite	Neurological Disease
L-Tyrosine is a non-essential amino acid which can inhibit **citrate synthase** activity in the posterior cortex.

HY-N0473S8

L-Tyrosine-d2	Endogenous Metabolite	Neurological Disease
L-Tyrosine-d₂ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-134136

Octanoyl Coenzyme A	Endogenous Metabolite	Metabolic Disease
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

HY-134136B

Octanoyl coenzyme A triammonium	Biochemical Assay Reagents	Metabolic Disease
Octanoyl coenzyme A triammonium is a medium-chain acyl coenzyme A. Octanoyl coenzyme A triammonium can inhibit **citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀** values of 0.4-1.6 mM .

HY-N0473S9

L-Tyrosine-d7	Endogenous Metabolite	Neurological Disease
L-Tyrosine-d₇ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S14

L-Tyrosine-d5	Endogenous Metabolite
L-Tyrosine-d₅ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S15

L-Tyrosine-d3	Endogenous Metabolite
L-Tyrosine-d₃ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S1

L-Tyrosine-15N	Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹⁵N is the ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S10

L-Tyrosine-d2-1	Endogenous Metabolite	Neurological Disease
L-Tyrosine-d₂-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S12

L-Tyrosine-17O	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹⁷O is the ¹⁷O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S4

L-Tyrosine-13C	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S13

L-Tyrosine-d2-2	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine-d₂-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S

L-Tyrosine-d4	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
L-Tyrosine-d₄ is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].

HY-N0473S2

L-Tyrosine-13C6	Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹³C₆ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S3

L-Tyrosine-13C9	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹³C₉ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S5

L-Tyrosine-4-13C	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine-4- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S7

L-Tyrosine-1-13C	Endogenous Metabolite	Neurological Disease
L-Tyrosine-1- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S6

L-Tyrosine-3,5-13C2	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine-3,5- ¹³C₂ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S11

L-Tyrosine-15N,d7	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹⁵N,d₇ is the deuterium and ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S16

L-Tyrosine-13C,15N	Endogenous Metabolite	Neurological Disease
L-Tyrosine- ¹³C, ¹⁵N is the ¹³C and ¹⁵N labeled L-Tyrosine[1]. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[2].

Cat. No.	Product Name	Type

HY-134136A

Octanoyl coenzyme A lithium	Biochemical Assay Reagents
Octanoyl coenzyme A lithium is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A lithium can inhibit **citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀** values of 0.4-1.6 mM .

HY-P2739

**Citrate synthase**	Biochemical Assay Reagents
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .

HY-134136

Octanoyl Coenzyme A	Biochemical Assay Reagents
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

Cat. No.	Product Name	Target	Research Area

HY-P2739

**Citrate synthase**	Peptides	Others
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0473

L-Tyrosine 1 Publications Verification Tyrosine	Structural Classification Microorganisms Neurological Disease Classification of Application Fields Anti-aging Source classification Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
L-Tyrosine is a non-essential amino acid which can inhibit **citrate synthase** activity in the posterior cortex.

HY-134136

Octanoyl Coenzyme A	Structural Classification Natural Products Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Octanoyl coenzyme A is a fatty acyl coenzyme A derivative. Octanoyl coenzyme A can inhibit citrate synthase (CS) and glutamate dehydrogenase (GDH) with IC₅₀ values of 0.4-1.6 mM .

Species:	Human (2)
Tag:	His (2) SUMO (1)
Source:	Sf9 insect cells (1) E. coli (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74251

	Citrate Synthase/CS Protein, Human (sf9, His) citrate synthase, mitochondrial; citrate (Si)-synthase; CS	Human	Sf9 insect cells
	Citrate Synthase (CS) is a key enzyme in carbohydrate metabolism, specifically in the tricarboxylic acid (TCA) cycle, where it catalyzes the conversion of oxaloacetate and acetyl-CoA to form citrate. This enzymatic process represents the first and crucial step in the TCA cycle, which is fundamental to cellular energy production. By initiating the cycle and facilitating the condensation of acetyl-CoA with oxaloacetate, CS plays a central role in channeling metabolic intermediates towards the production of energy-rich molecules. This step not only generates citrate but also sets the stage for subsequent reactions in the TCA cycle, ultimately contributing to the efficient extraction of energy from carbohydrates and other metabolic substrates. The activity of CS is pivotal in maintaining cellular energy homeostasis and ensuring the proper functioning of aerobic metabolism. Citrate Synthase/CS Protein, Human (sf9, His) is the recombinant human-derived Citrate Synthase/CS protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Citrate Synthase/CS Protein, Human (sf9, His) is 439 a.a., with molecular weight of ~46 kDa.

HY-P72070

	ACLY Protein, Human (His-SUMO) ACL; Acly; ACLY_HUMAN; ATP citrate pro-S; lyase; ATP citrate lyase; ATP citrate synthase; ATP-citrate pro-S-; -lyase; ATP-citrate synthase; ATPcitrate synthase; ATPCL; citrate cleavage enzyme; CLATP; OTTHUMP00000164773	Human	E. coli
	ACLY Protein, Human (His-SUMO) is an important enzyme in the cholesterol biosynthetic pathway. ACLY produces acetyl-CoA (AcCoA) from mitochondrial citrate for cholesterol and fatty acid biosynthesis.


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Cat. No.	Product Name	Chemical Structure

HY-N0473S8

L-Tyrosine-d2

L-Tyrosine-d₂ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S9

L-Tyrosine-d7

L-Tyrosine-d₇ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S15

L-Tyrosine-d3

L-Tyrosine-d₃ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S1

L-Tyrosine-15N

L-Tyrosine- ¹⁵N is the ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S14

L-Tyrosine-d5

L-Tyrosine-d₅ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S10

L-Tyrosine-d2-1

L-Tyrosine-d₂-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S12

L-Tyrosine-17O

L-Tyrosine- ¹⁷O is the ¹⁷O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S4

L-Tyrosine-13C

L-Tyrosine- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S13

L-Tyrosine-d2-2

L-Tyrosine-d₂-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S

L-Tyrosine-d4

L-Tyrosine-d₄ is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].
HY-N0473S2

L-Tyrosine-13C6

L-Tyrosine- ¹³C₆ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S3

L-Tyrosine-13C9

L-Tyrosine- ¹³C₉ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S5

L-Tyrosine-4-13C

L-Tyrosine-4- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S7

L-Tyrosine-1-13C

L-Tyrosine-1- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
HY-N0473S6

L-Tyrosine-3,5-13C2

L-Tyrosine-3,5- ¹³C₂ is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d2
L-Tyrosine-d₂ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d7
L-Tyrosine-d₇ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d3
L-Tyrosine-d₃ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-15N
L-Tyrosine- ¹⁵N is the ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d5
L-Tyrosine-d₅ is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d2-1
L-Tyrosine-d₂-1 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-17O
L-Tyrosine- ¹⁷O is the ¹⁷O-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-13C
L-Tyrosine- ¹³C is the ¹³C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d2-2
L-Tyrosine-d₂-2 is the deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

L-Tyrosine-d4
L-Tyrosine-d₄ is a deuterium labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[1].

HY-N0473S11

L-Tyrosine-15N,d7
L-Tyrosine- ¹⁵N,d₇ is the deuterium and ¹⁵N-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.

HY-N0473S16

L-Tyrosine-13C,15N
L-Tyrosine- ¹³C, ¹⁵N is the ¹³C and ¹⁵N labeled L-Tyrosine[1]. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex[2].

Cat. No.	Product Name	Application	Reactivity

HY-P80560

ATP Citrate Lyase Antibody (YA829) ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; citrate cleavage enzyme	WB, ICC/IF, FC	Human, Mouse, Monkey
ATP Citrate Lyase Antibody (YA829) is a non-conjugated and Mouse origined monoclonal antibody about 121 kDa, targeting to ATP Citrate Lyase (3D9). It can be used for WB,ICC/IF,FC assays with tag free, in the background of Human, Mouse, Monkey.

HY-P83057

Citrate Synthetase Antibody (YA2802)

citrate synthase; citrate synthase; mitochondrial; Cs
WB, IHC-F, IHC-P, ICC/IF, IP Human, Rat

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Recombinant Proteins

Isotope-Labeled Compounds

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citrate synthase

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

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Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

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